Susan E Crawford Selected Research

Prostatic Neoplasms (Prostate Cancer)

5/2022	Ephrin B Activate Src Family Kinases in Fibroblasts Inducing Stromal Remodeling in Prostate Cancer.
1/2021	Loss of ephrin B2 receptor (EPHB2) sets lipid rheostat by regulating proteins DGAT1 and ATGL inducing lipid droplet storage in prostate cancer cells.
12/2019	Lipid droplet velocity is a microenvironmental sensor of aggressive tumors regulated by V-ATPase and PEDF.
1/2019	Tyrosine kinase inhibitor therapy prescribed for non-urologic diseases can modify PSA titers in urology patients.
11/2018	Elevation of Stromal-Derived Mediators of Inflammation Promote Prostate Cancer Progression in African-American Men.
11/2018	PEDF regulates plasticity of a novel lipid-MTOC axis in prostate cancer-associated fibroblasts.
8/2017	A genetic variant near GATA3 implicated in inherited susceptibility and etiology of benign prostatic hyperplasia (BPH) and lower urinary tract symptoms (LUTS).
9/2015	MRS measured fatty acid composition of periprostatic adipose tissue correlates with pathological measures of prostate cancer aggressiveness.
12/2010	Overexpression of transforming growth factor β1 in malignant prostate cells is partly caused by a runaway of TGF-β1 auto-induction mediated through a defective recruitment of protein phosphatase 2A by TGF-β type I receptor.
7/2010	Thrombospondin-1 regulates the normal prostate in vivo through angiogenesis and TGF-beta activation.

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Susan E Crawford Research Topics

Disease

27	Neoplasms (Cancer) 05/2022 - 04/2002
11	Prostatic Neoplasms (Prostate Cancer) 05/2022 - 08/2004
8	Carcinogenesis 05/2022 - 04/2002
6	Inflammation (Inflammations) 01/2024 - 10/2004
5	Colonic Neoplasms (Colon Cancer) 11/2021 - 01/2016
5	Mucocutaneous Lymph Node Syndrome (Kawasaki Disease) 02/2008 - 04/2003
4	Obesity 11/2021 - 12/2013
3	Breast Neoplasms (Breast Cancer) 01/2017 - 07/2006
3	Pancreatic Neoplasms (Pancreatic Cancer) 10/2012 - 01/2007
3	Hypoxia (Hypoxemia) 07/2010 - 09/2003
3	Infections 11/2009 - 04/2006
3	Vascular Remodeling 07/2008 - 04/2005
3	Aneurysm (Aneurysms) 10/2004 - 04/2003
2	Retinal Degeneration 07/2022 - 01/2020
2	Adenocarcinoma 01/2017 - 05/2011
2	Hepatocellular Carcinoma (Hepatoma) 01/2015 - 01/2008
2	Metabolic Syndrome (Dysmetabolic Syndrome X) 04/2014 - 12/2012
2	Wilms Tumor (Wilm's Tumor) 08/2006 - 03/2003
2	Fibrosis (Cirrhosis) 08/2005 - 09/2003
2	Pathologic Constriction (Stenosis) 08/2005 - 09/2003
2	Vascular System Injuries 08/2005 - 04/2005
2	Neoplasm Metastasis (Metastasis) 08/2004 - 04/2002
1	Colitis 01/2024
1	Body Weight (Weight, Body) 01/2020
1	Atrophy 01/2020
1	Infarction (Infarctions) 06/2019
1	Urologic Diseases (Urinary Tract Disease) 01/2019
1	Drug-Related Side Effects and Adverse Reactions 01/2019
1	BCR-ABL Positive Chronic Myelogenous Leukemia (Chronic Myelogenous Leukemia) 01/2019
1	Urinary Bladder Neoplasms (Bladder Cancer) 01/2018
1	Microsatellite Instability 11/2017
1	Endometrial Neoplasms (Endometrial Cancer) 01/2017
1	Endometrial Hyperplasia 01/2017

Drug/Important Bio-Agent (IBA)

16	pigment epithelium-derived factorIBA 07/2022 - 03/2003
12	Proteins (Proteins, Gene)FDA Link 07/2022 - 01/2004
7	LipidsIBA 01/2021 - 03/2004
7	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 07/2008 - 09/2003
5	AntibodiesIBA 04/2008 - 03/2003
4	Lipase (Acid Lipase)FDA Link 11/2021 - 12/2013
4	Messenger RNA (mRNA)IBA 01/2019 - 08/2004
3	Biomarkers (Surrogate Marker)IBA 01/2019 - 11/2014
3	AzoxymethaneIBA 01/2017 - 07/2011
3	Fatty Acids (Saturated Fatty Acids)IBA 09/2015 - 01/2008
3	Matrix Metalloproteinases (MMPs)IBA 10/2012 - 04/2003
3	Thrombospondin 1IBA 07/2010 - 04/2002
3	AndrogensIBA 07/2010 - 06/2003
3	Clindamycin (Cleocin)FDA LinkGeneric 11/2009 - 04/2006
2	EphrinsIBA 05/2022 - 01/2021
2	Protein-Tyrosine Kinases (Tyrosine Kinase)IBA 01/2021 - 07/2006
2	Triglycerides (Triacylglycerol)IBA 01/2021 - 01/2017
2	Adenosine Triphosphatases (ATPase)IBA 12/2019 - 05/2011
2	Indicators and Reagents (Reagents)IBA 01/2019 - 01/2004
2	Conditioned Culture MediaIBA 11/2018 - 06/2004
2	LeptinIBA 01/2017 - 12/2013
2	RNA (Ribonucleic Acid)IBA 01/2017 - 02/2008
2	Estrogens (Estrogen)FDA Link 01/2017 - 03/2003
2	Perilipin-2IBA 01/2016 - 06/2013
2	Peroxidase (Myeloperoxidase)IBA 11/2015 - 05/2013
2	Peptides (Polypeptides)IBA 01/2015 - 04/2002
2	Insulin (Novolin)FDA Link 04/2014 - 12/2012
2	Angiogenesis InhibitorsIBA 07/2008 - 11/2005
2	Vascular Endothelial Growth Factor Receptors (VEGF Receptors)IBA 04/2008 - 11/2005
2	AntigensIBA 10/2005 - 08/2004
2	Phenobarbital (Luminal)FDA Link 08/2005 - 09/2003
2	OsteopontinIBA 08/2005 - 04/2005
2	Factor VIII (Coagulation Factor VIII)IBA 03/2003 - 03/2003
1	Fenofibrate (CiL)FDA LinkGeneric 01/2024
1	Peroxisome Proliferator-Activated Receptors (PPAR)IBA 01/2024
1	CollagenIBA 05/2022
1	LigandsIBA 05/2022
1	Eph Family Receptors (Eph Receptors)IBA 05/2022
1	src-Family KinasesIBA 05/2022
1	Oleic Acid (Oleate)IBA 11/2021
1	EphB2 ReceptorIBA 01/2021
1	Ephrin-B2 (Ephrin B2)IBA 01/2021
1	Capsules (Microcapsules)IBA 01/2020
1	sodium iodateIBA 01/2020
1	Retinaldehyde (Retinal)IBA 01/2020
1	Proton Pumps (Proton Pump)IBA 12/2019
1	ThrombospondinsIBA 01/2019
1	Tyrosine Kinase InhibitorsIBA 01/2019
1	alpha-N-acetylneuraminate alpha-2,8-sialyltransferaseIBA 01/2019
1	Prostate-Specific Antigen (Semenogelase)IBA 01/2019
1	Imatinib Mesylate (Gleevec)FDA Link 01/2019
1	IntegrinsIBA 01/2019
1	Small Interfering RNA (siRNA)IBA 01/2019
1	nilotinib FDA Link 01/2019
1	Metalloproteases (Metalloproteinases)IBA 01/2019
1	Inflammation MediatorsIBA 11/2018
1	ChromatinIBA 01/2018
1	CarcinogensIBA 01/2018
1	Dutasteride (Avodart)FDA Link 08/2017
1	Adenosine Triphosphate (ATP)IBA 01/2017
1	Dextran SulfateIBA 01/2017
1	Transcription Factors (Transcription Factor)IBA 01/2016
1	ErbB Receptors (EGF Receptor)IBA 01/2016
1	Epidermal Growth Factor (EGF)IBA 01/2016

Therapy/Procedure

7	Therapeutics 01/2019 - 03/2004
2	Prostatectomy (Retropubic Prostatectomy) 09/2015 - 01/2004
2	Transplantation 06/2004 - 03/2004